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Whole-genome methylation analysis reveals epigenetic variation between wild-type and nontransgenic cloned, ASMT transgenic cloned dairy goats generated by the somatic cell nuclear transfer

BACKGROUND: SCNT (somatic cell nuclear transfer) is of great significance to biological research and also to the livestock breeding. However, the survival rate of the SCNT cloned animals is relatively low compared to other transgenic methods. This indicates the potential epigenetic variations betwee...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Zhou, Wendi, Liu, Haijun, Cui, Xudai, Ma, Wenkui, Wu, Haixin, Li, Guangdong, Wang, Likai, Zhang, Jinlong, Zhang, Xiaosheng, Ji, Pengyun, Lian, Zhengxing, Liu, Guoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701027/
https://www.ncbi.nlm.nih.gov/pubmed/36434676
http://dx.doi.org/10.1186/s40104-022-00764-6