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Noninvasive detection of pancreatic ductal adenocarcinoma using the methylation signature of circulating tumour DNA

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) has the lowest overall survival rate primarily due to the late onset of symptoms and rapid progression. Reliable and accurate tests for early detection are lacking. We aimed to develop a noninvasive test for early PDAC detection by capturing the ci...

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Detalles Bibliográficos
Autores principales: Wu, Huanwen, Guo, Shiwei, Liu, Xiaoding, Li, Yatong, Su, Zhixi, He, Qiye, Liu, Xiaoqian, Zhang, Zhiwen, Yu, Lianyuan, Shi, Xiaohan, Gao, Suizhi, Wang, Huan, Pan, Yaqi, Ma, Chengcheng, Liu, Rui, Dai, Menghua, Jin, Gang, Liang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701032/
https://www.ncbi.nlm.nih.gov/pubmed/36434648
http://dx.doi.org/10.1186/s12916-022-02647-z