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Genetic variant in SPAG16 is associated with the susceptibility of ACPA-positive rheumatoid arthritis possibly via regulation of MMP-3

OBJECTIVES: In two previously published genome-wide association studies, a cluster of variants of sperm-associated antigen16 (SPAG16) were reported to be associated with the radiological progression rate of ACPA-positive rheumatoid arthritis (RA) patients from North American and Southern European an...

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Detalles Bibliográficos
Autores principales: Lin, Qingxi, Zhou, Bingxiang, Song, Xiaoxiao, Ye, Wei, Li, Qinglong, Shi, Tong, Cheng, Chen, Li, Yetian, Wei, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701044/
https://www.ncbi.nlm.nih.gov/pubmed/36434627
http://dx.doi.org/10.1186/s13018-022-03405-w