A pipeline for malignancy and therapy agnostic assessment of cancer drug response using cell mass measurements

Functional precision medicine offers a promising complement to genomics-based cancer therapy guidance by testing drug efficacy directly on a patient’s tumor cells. Here, we describe a workflow that utilizes single-cell mass measurements with inline brightfield imaging and machine-learning based imag...

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Detalles Bibliográficos
Autores principales: Kimmerling, Robert J., Stevens, Mark M., Olcum, Selim, Minnah, Anthony, Vacha, Madeleine, LaBella, Rachel, Ferri, Matthew, Wasserman, Steven C., Fujii, Juanita, Shaheen, Zayna, Sundaresan, Srividya, Ribadeneyra, Drew, Jayabalan, David S., Agte, Sarita, Aleman, Adolfo, Criscitiello, Joseph A., Niesvizky, Ruben, Luskin, Marlise R., Parekh, Samir, Rosenbaum, Cara A., Tamrazi, Anobel, Reid, Clifford A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701192/
https://www.ncbi.nlm.nih.gov/pubmed/36435843
http://dx.doi.org/10.1038/s42003-022-04270-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701192/
https://www.ncbi.nlm.nih.gov/pubmed/36435843
http://dx.doi.org/10.1038/s42003-022-04270-3

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