Versatile and efficient genome editing with Neisseria cinerea Cas9

The CRISPR/Cas9 system is a versatile genome editing platform in biotechnology and therapeutics. However, the requirement of protospacer adjacent motifs (PAMs) limits the genome targeting scope. To expand this repertoire, we revisited and engineered a compact Cas9 orthologue derived from Neisseria c...

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Detalles Bibliográficos
Autores principales: Liu, Zhiquan, Chen, Siyu, Xie, Wanhua, Yu, Hao, Lai, Liangxue, Li, Zhanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701194/
https://www.ncbi.nlm.nih.gov/pubmed/36435853
http://dx.doi.org/10.1038/s42003-022-04258-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701194/
https://www.ncbi.nlm.nih.gov/pubmed/36435853
http://dx.doi.org/10.1038/s42003-022-04258-z

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