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Structural basis for lipid and copper regulation of the ABC transporter MsbA
A critical step in lipopolysaccharide (LPS) biogenesis involves flipping lipooligosaccharide, an LPS precursor, from the cytoplasmic to the periplasmic leaflet of the inner membrane, an operation carried out by the ATP-binding cassette transporter MsbA. Although LPS binding to the inner cavity of Ms...
Autores principales: | Lyu, Jixing, Liu, Chang, Zhang, Tianqi, Schrecke, Samantha, Elam, Nicklaus P., Packianathan, Charles, Hochberg, Georg K. A., Russell, David, Zhao, Minglei, Laganowsky, Arthur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701195/ https://www.ncbi.nlm.nih.gov/pubmed/36435815 http://dx.doi.org/10.1038/s41467-022-34905-2 |
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