Cargando…

Mutual regulation between phosphofructokinase 1 platelet isoform and VEGF promotes glioblastoma tumor growth

Glioblastoma (GBM) is a highly vascular malignant brain tumor that overexpresses vascular endothelial growth factor (VEGF) and phosphofructokinase 1 platelet isoform (PFKP), which catalyzes a rate-limiting reaction in glycolysis. However, whether PFKP and VEGF are reciprocally regulated during GBM t...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Je Sun, Shi, YuJie, Park, Su Hwan, Jeon, So Mi, Zhang, Chuanbao, Park, Yun-Yong, Liu, Rui, Li, Jing, Cho, Wan-Seob, Du, Linyong, Lee, Jong-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701207/
https://www.ncbi.nlm.nih.gov/pubmed/36435833
http://dx.doi.org/10.1038/s41419-022-05449-6