Cargando…

ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression

Chronic inflammation and an immunosuppressive microenvironment promote prostate cancer (PCa) progression and diminish the response to immune checkpoint blockade (ICB) therapies. However, it remains unclear how and to what extent these two events are coordinated. Here, we show that ARID1A, a subunit...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ni, Liu, Qiuli, Han, Ying, Pei, Siyu, Cheng, Bisheng, Xu, Junyu, Miao, Xiang, Pan, Qiang, Wang, Hanling, Guo, Jiacheng, Wang, Xuege, Zhang, Guoying, Lian, Yannan, Zhang, Wei, Zang, Yi, Tan, Minjia, Li, Qintong, Wang, Xiaoming, Xiao, Yichuan, Hu, Guohong, Jiang, Jun, Huang, Hai, Qin, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701216/
https://www.ncbi.nlm.nih.gov/pubmed/36435834
http://dx.doi.org/10.1038/s41467-022-34871-9