Molecular basis for glycan recognition and reaction priming of eukaryotic oligosaccharyltransferase

Oligosaccharyltransferase (OST) is the central enzyme of N-linked protein glycosylation. It catalyzes the transfer of a pre-assembled glycan, GlcNAc(2)Man(9)Glc(3), from a dolichyl-pyrophosphate donor to acceptor sites in secretory proteins in the lumen of the endoplasmic reticulum. Precise recognit...

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Detalles Bibliográficos
Autores principales: Ramírez, Ana S., de Capitani, Mario, Pesciullesi, Giorgio, Kowal, Julia, Bloch, Joël S., Irobalieva, Rossitza N., Reymond, Jean-Louis, Aebi, Markus, Locher, Kaspar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701220/
https://www.ncbi.nlm.nih.gov/pubmed/36435935
http://dx.doi.org/10.1038/s41467-022-35067-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701220/
https://www.ncbi.nlm.nih.gov/pubmed/36435935
http://dx.doi.org/10.1038/s41467-022-35067-x

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