Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1

Forkhead box H1 (FoxH1) is an essential maternal pioneer factor during embryonic development that binds to specific GG/GT-containing DNA target sequences. Here we have determined high-resolution structures of three FoxH1 proteins (from human, frog and fish species) and four DNAs to clarify the way i...

Descripción completa

Detalles Bibliográficos
Autores principales: Pluta, Radoslaw, Aragón, Eric, Prescott, Nicholas A., Ruiz, Lidia, Mees, Rebeca A., Baginski, Blazej, Flood, Julia R., Martin-Malpartida, Pau, Massagué, Joan, David, Yael, Macias, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701222/
https://www.ncbi.nlm.nih.gov/pubmed/36435807
http://dx.doi.org/10.1038/s41467-022-34925-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701222/
https://www.ncbi.nlm.nih.gov/pubmed/36435807
http://dx.doi.org/10.1038/s41467-022-34925-y

Ejemplares similares