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Kinetochore- and chromosome-driven transition of microtubules into bundles promotes spindle assembly

Mitotic spindle assembly is crucial for chromosome segregation and relies on bundles of microtubules that extend from the poles and overlap in the middle. However, how these structures form remains poorly understood. Here we show that overlap bundles arise through a network-to-bundles transition dri...

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Detalles Bibliográficos
Autores principales: Matković, Jurica, Ghosh, Subhadip, Ćosić, Mateja, Eibes, Susana, Barišić, Marin, Pavin, Nenad, Tolić, Iva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701229/
https://www.ncbi.nlm.nih.gov/pubmed/36435852
http://dx.doi.org/10.1038/s41467-022-34957-4