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Rad52’s DNA annealing activity drives template switching associated with restarted DNA replication
It is thought that many of the simple and complex genomic rearrangements associated with congenital diseases and cancers stem from mistakes made during the restart of collapsed replication forks by recombination enzymes. It is hypothesised that this recombination-mediated restart process transitions...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701231/ https://www.ncbi.nlm.nih.gov/pubmed/36435847 http://dx.doi.org/10.1038/s41467-022-35060-4 |