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Loss of Gap Junction Factor Connexin 43 Results in an Increase of Exosomal Tetraspanins in Human Lung Cancer Cell Line A549

Gap junctions (GJs) and small extracellular vesicles such as exosomes are two fundamental intercellular communication (IC) mechanisms. We tested the hypothesis that the two IC mechanisms are connected by gene editing to inactivate a ubiquitously expression GJ factor (i.e., Cx43) in the human lung ca...

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Detalles Bibliográficos
Autores principales: Fleck, Alexandra P, Flotte, Ariel B, Si, Edward P, Mu, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701318/
https://www.ncbi.nlm.nih.gov/pubmed/36447528
http://dx.doi.org/10.17912/micropub.biology.000683