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Chronotherapeutic neuroprotective effect of verapamil against lipopolysaccharide-induced neuroinflammation in mice through modulation of calcium-dependent genes

BACKGROUND: Neuroinflammation is a major mechanism in neurodegenerative diseases such as Alzheimer’s disease (AD), which is a major healthcare problem. Notwithstanding of ample researches figured out possible molecular mechanisms underlying the pathophysiology of AD, there is no definitive therapeut...

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Detalles Bibliográficos
Autores principales: Mosalam, Esraa M., Elberri, Aya Ibrahim, Sallam, Amany Said, Salem, Heba Rady, Metwally, Ebtehal M., Abdallah, Mahmoud S., Shaldam, Moataz A., Mansour, Hend E. Abo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701385/
https://www.ncbi.nlm.nih.gov/pubmed/36435759
http://dx.doi.org/10.1186/s10020-022-00564-8