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Paxlovid accelerates cartilage degeneration and senescence through activating endoplasmic reticulum stress and interfering redox homeostasis
BACKGROUND: The COVID-19 pandemic has become a huge threat to human health, infecting millions of people worldwide and causing enormous economic losses. Many novel small molecule drugs have been developed to treat patients with COVID-19, including Paxlovid, which block the synthesis of virus-related...
Autores principales: | Kong, Keyu, Chang, Yongyun, Qiao, Hua, Zhao, Chen, Chen, Xuzhuo, Rong, Kewei, Zhang, Pu, Jin, Minghao, Zhang, Jingwei, Li, Huiwu, Zhai, Zanjing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701426/ https://www.ncbi.nlm.nih.gov/pubmed/36435786 http://dx.doi.org/10.1186/s12967-022-03770-4 |
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