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Integrated Network Pharmacology Analysis and Experimental Validation to Investigate the Molecular Mechanism of Triptolide in the Treatment of Membranous Nephropathy

BACKGROUND: Triptolide, a major active ingredient isolated from Tripterygium wilfordii Hook f., is effective in the treatment of membranous nephropathy (MN); however, its pharmacological mechanism of action has not yet been clarified. We applied an approach that integrated network pharmacology and e...

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Detalles Bibliográficos
Autores principales: Zhang, Ping Na, Tang, Jing Yi, Yang, Ke Zhen, Zheng, Qi Yan, Dong, Zhao Cheng, Geng, Yun Ling, Liu, Yu Ning, Liu, Wei Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701458/
https://www.ncbi.nlm.nih.gov/pubmed/36448035
http://dx.doi.org/10.2147/DDDT.S386031