Systematic generation and imaging of tandem repeats reveal base-pairing properties that promote RNA aggregation

A common pathological feature of RNAs containing expanded repeat sequences is their propensity to aggregate in cells. While some repeat RNA aggregates have been shown to cause toxicity by sequestering RNA-binding proteins, the molecular mechanism of aggregation remains unclear. Here, we devised an e...

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Detalles Bibliográficos
Autores principales: Isiktas, Atagun U., Eshov, Aziz, Yang, Suzhou, Guo, Junjie U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701603/
https://www.ncbi.nlm.nih.gov/pubmed/36452875
http://dx.doi.org/10.1016/j.crmeth.2022.100334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701603/
https://www.ncbi.nlm.nih.gov/pubmed/36452875
http://dx.doi.org/10.1016/j.crmeth.2022.100334

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