Normalization benchmark of ATAC-seq datasets shows the importance of accounting for GC-content effects

The assay for transposase-accessible chromatin using sequencing (ATAC-seq) allows the study of epigenetic regulation of gene expression by assessing chromatin configuration for an entire genome. Despite its popularity, there have been limited studies investigating the analytical challenges related t...

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Detalles Bibliográficos
Autores principales: Van den Berge, Koen, Chou, Hsin-Jung, Roux de Bézieux, Hector, Street, Kelly, Risso, Davide, Ngai, John, Dudoit, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701614/
https://www.ncbi.nlm.nih.gov/pubmed/36452861
http://dx.doi.org/10.1016/j.crmeth.2022.100321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701614/
https://www.ncbi.nlm.nih.gov/pubmed/36452861
http://dx.doi.org/10.1016/j.crmeth.2022.100321

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