Cargando…
Normalization benchmark of ATAC-seq datasets shows the importance of accounting for GC-content effects
The assay for transposase-accessible chromatin using sequencing (ATAC-seq) allows the study of epigenetic regulation of gene expression by assessing chromatin configuration for an entire genome. Despite its popularity, there have been limited studies investigating the analytical challenges related t...
Autores principales: | Van den Berge, Koen, Chou, Hsin-Jung, Roux de Bézieux, Hector, Street, Kelly, Risso, Davide, Ngai, John, Dudoit, Sandrine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701614/ https://www.ncbi.nlm.nih.gov/pubmed/36452861 http://dx.doi.org/10.1016/j.crmeth.2022.100321 |
Ejemplares similares
-
GC-Content Normalization for RNA-Seq Data
por: Risso, Davide, et al.
Publicado: (2011) -
Trajectory-based differential expression analysis for single-cell sequencing data
por: Van den Berge, Koen, et al.
Publicado: (2020) -
A Latent Activated Olfactory Stem Cell State Revealed by Single Cell Transcriptomic and Epigenomic Profiling
por: den Berge, Koen Van, et al.
Publicado: (2023) -
CALDERA: finding all significant de Bruijn subgraphs for bacterial GWAS
por: Roux de Bézieux, Hector, et al.
Publicado: (2022) -
Benchmarking algorithms for joint integration of unpaired and paired single-cell RNA-seq and ATAC-seq data
por: Lee, Michelle Y. Y., et al.
Publicado: (2023)