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Derivation of nociceptive sensory neurons from hiPSCs with early patterning and temporally controlled NEUROG2 overexpression

Despite development of protocols to differentiate human pluripotent stem cells (hPSCs), those used to produce sensory neurons remain difficult to replicate and result in heterogenous populations. There is a growing clinical burden of chronic pain conditions, highlighting the need for relevant human...

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Detalles Bibliográficos
Autores principales: Plumbly, William, Patikas, Nikolaos, Field, Sarah F., Foskolou, Stefanie, Metzakopian, Emmanouil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701618/
https://www.ncbi.nlm.nih.gov/pubmed/36452863
http://dx.doi.org/10.1016/j.crmeth.2022.100341