Cargando…

Assessment of spatial transcriptomics for oncology discovery

Tumor heterogeneity is a major challenge for oncology drug discovery and development. Understanding of the spatial tumor landscape is key to identifying new targets and impactful model systems. Here, we test the utility of spatial transcriptomics (ST) for oncology discovery by profiling 40 tissue se...

Descripción completa

Detalles Bibliográficos
Autores principales: Lyubetskaya, Anna, Rabe, Brian, Fisher, Andrew, Lewin, Anne, Neuhaus, Isaac, Brett, Constance, Brett, Todd, Pereira, Ethel, Golhar, Ryan, Kebede, Sami, Font-Tello, Alba, Mosure, Kathy, Van Wittenberghe, Nicholas, Mavrakis, Konstantinos J., MacIsaac, Kenzie, Chen, Benjamin J., Drokhlyansky, Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701619/
https://www.ncbi.nlm.nih.gov/pubmed/36452860
http://dx.doi.org/10.1016/j.crmeth.2022.100340