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Electron microscopy of desmosomal structures in the pemphigus human skin organ culture model

Pemphigus is a chronic autoimmune skin blistering disease, characterized by acantholysis and by the production of autoantibodies directed against the structural desmosomal proteins desmoglein 1 (DSG1) and/or DSG3. Model systems allow the identification and testing of new therapeutic targets. Here, w...

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Detalles Bibliográficos
Autores principales: Radine, Uta Katharina, Bumiller-Bini Hoch, Valéria, Boldt, Angelica B. Winter, Zillikens, Detlef, Ludwig, Ralf J., Hammers, Christoph M., Klinger, Matthias, Hundt, Jennifer E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701718/
https://www.ncbi.nlm.nih.gov/pubmed/36452895
http://dx.doi.org/10.3389/fmed.2022.997387