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Tandem mass tag-based proteomic profiling revealed potential therapeutic targets and mechanisms of liraglutide for the treatment of impaired glucose tolerance

OBJECTIVE: Based on the tandem mass tag (TMT) technique, our study investigated the potential therapeutic targets of Liraglutide (LIRA) on streptozotocin (STZ) induced impaired glucose tolerance (IGT) in rats and discuss the biological mechanism of the drug against IGT. METHODS: 10 rats were randoml...

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Detalles Bibliográficos
Autores principales: Guo, Qiuyue, Han, Cong, Xu, Yunsheng, Chen, Qingguang, Han, Xu, Zhao, Sen, Li, Jie, Lu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701722/
https://www.ncbi.nlm.nih.gov/pubmed/36452319
http://dx.doi.org/10.3389/fendo.2022.1031019