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Fexinidazole interferes with the growth and structural organization of Trypanosoma cruzi

Fexinidazole (FEX) is a heterocyclic compound and constitutes the first 100% oral treatment drug for African trypanosomiasis. Its effectiveness against Trypanosoma brucei encouraged the investigation of its antiparasitic potential against T. cruzi, the aetiological agent of Chagas disease. Although...

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Detalles Bibliográficos
Autores principales: Zuma, Aline Araujo, de Souza, Wanderley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701812/
https://www.ncbi.nlm.nih.gov/pubmed/36437273
http://dx.doi.org/10.1038/s41598-022-23941-z