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Fexinidazole interferes with the growth and structural organization of Trypanosoma cruzi
Fexinidazole (FEX) is a heterocyclic compound and constitutes the first 100% oral treatment drug for African trypanosomiasis. Its effectiveness against Trypanosoma brucei encouraged the investigation of its antiparasitic potential against T. cruzi, the aetiological agent of Chagas disease. Although...
Autores principales: | Zuma, Aline Araujo, de Souza, Wanderley |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9701812/ https://www.ncbi.nlm.nih.gov/pubmed/36437273 http://dx.doi.org/10.1038/s41598-022-23941-z |
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