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High tumor mutation burden indicates better prognosis in colorectal cancer patients with KRAS mutations

OBJECTIVE: Colorectal cancer (CRC) is a common type of malignant tumor of the digestive tract. Tumor mutation burden (TMB) is a potential prognostic indicator of numerous malignant tumors. This study investigated the prognostic value of TMB in CRC. METHODS: This study analyzed the clinical and somat...

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Detalles Bibliográficos
Autores principales: Wang, Jianlei, Song, Jianping, Liu, Zeyang, Zhang, Tingxiao, Liu, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702324/
https://www.ncbi.nlm.nih.gov/pubmed/36452508
http://dx.doi.org/10.3389/fonc.2022.1015308