Establishment of transgenic pigs overexpressing human PKD2-D511V mutant

Numerous missense mutations have been reported in autosomal dominant polycystic kidney disease which is one of the most common renal genetic disorders. The underlying mechanism for cystogenesis is still elusive, partly due to the lack of suitable animal models. Currently, we tried to establish a por...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Xu, Saifei, Jin, Qiao, Luo, Jianing, Gao, Ce, Jayaprakash, Sakthidasan, Wang, Huanan, Zhuang, Lenan, He, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702356/
https://www.ncbi.nlm.nih.gov/pubmed/36452154
http://dx.doi.org/10.3389/fgene.2022.1059682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702356/
https://www.ncbi.nlm.nih.gov/pubmed/36452154
http://dx.doi.org/10.3389/fgene.2022.1059682

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