Structure, evolution and expression of zebrafish cartilage oligomeric matrix protein (COMP, TSP5). CRISPR-Cas mutants show a dominant phenotype in myosepta

COMP (Cartilage Oligomeric Matrix Protein), also named thrombospondin-5, is a member of the thrombospondin family of extracellular matrix proteins. It is of clinical relevance, as in humans mutations in COMP lead to chondrodysplasias. The gene encoding zebrafish Comp is located on chromosome 11 in s...

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Detalles Bibliográficos
Autores principales: Forte-Gomez, Helena Fabiana, Gioia, Roberta, Tonelli, Francesca, Kobbe, Birgit, Koch, Peter, Bloch, Wilhelm, Paulsson, Mats, Zaucke, Frank, Forlino, Antonella, Wagener, Raimund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702538/
https://www.ncbi.nlm.nih.gov/pubmed/36452329
http://dx.doi.org/10.3389/fendo.2022.1000662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702538/
https://www.ncbi.nlm.nih.gov/pubmed/36452329
http://dx.doi.org/10.3389/fendo.2022.1000662

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