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Cdk8 attenuates lipogenesis by inhibiting SREBP-dependent transcription in Drosophila

Fine-tuning of lipogenic gene expression is important for the maintenance of long-term homeostasis of intracellular lipids. The SREBP family of transcription factors are master regulators that control the transcription of lipogenic and cholesterogenic genes, but the mechanisms modulating SREBP-depen...

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Detalles Bibliográficos
Autores principales: Li, Xiao, Zhang, Meng, Liu, Mengmeng, Liu, Tzu-Hao, Hemba-Waduge, Rajitha-Udakara-Sampath, Ji, Jun-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702540/
https://www.ncbi.nlm.nih.gov/pubmed/36305265
http://dx.doi.org/10.1242/dmm.049650