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Case report: Unique FLT4 variants associated with differential response to anlotinib in angiosarcoma

Angiosarcoma (AS) is a rare, clinically aggressive tumor with limited treatment options and a poor prognosis. Mutations involving the angiogenesis-related genesTP53, PTPRB, PLCG1, KDR as well as FLT4 amplification have been observed in AS. There is a potential therapeutic value of inhibition of the...

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Detalles Bibliográficos
Autores principales: Gu, Yuanyuan, Meng, Jing, Ju, Yongzhi, You, Xia, Sun, Tingting, Lu, Jun, Guan, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702819/
https://www.ncbi.nlm.nih.gov/pubmed/36452496
http://dx.doi.org/10.3389/fonc.2022.1027696