Cargando…

Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNA

BACKGROUND: As circulating DNA (cirDNA) is mainly detected as mononucleosome-associated circulating DNA (mono-N cirDNA) in blood, apoptosis has until now been considered as the main source of cirDNA. The mechanism of cirDNA release into the circulation, however, is still not fully understood. This w...

Descripción completa

Detalles Bibliográficos
Autores principales: Pisareva, Ekaterina, Mihalovičová, Lucia, Pastor, Brice, Kudriavtsev, Andrei, Mirandola, Alexia, Mazard, Thibault, Badiou, Stephanie, Maus, Ulrich, Ostermann, Lena, Weinmann-Menke, Julia, Neuberger, Elmo W. I., Simon, Perikles, Thierry, Alain R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9702877/
https://www.ncbi.nlm.nih.gov/pubmed/36443816
http://dx.doi.org/10.1186/s13073-022-01125-8