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HIV-1 Vpu restricts Fc-mediated effector functions in vivo

Non-neutralizing antibodies (nnAbs) can eliminate HIV-1-infected cells via antibody-dependent cellular cytotoxicity (ADCC) and were identified as a correlate of protection in the RV144 vaccine trial. Fc-mediated effector functions of nnAbs were recently shown to alter the course of HIV-1 infection i...

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Detalles Bibliográficos
Autores principales: Prévost, Jérémie, Anand, Sai Priya, Rajashekar, Jyothi Krishnaswamy, Zhu, Li, Richard, Jonathan, Goyette, Guillaume, Medjahed, Halima, Gendron-Lepage, Gabrielle, Chen, Hung-Ching, Chen, Yaozong, Horwitz, Joshua A., Grunst, Michael W., Zolla-Pazner, Susan, Haynes, Barton F., Burton, Dennis R., Flavell, Richard A., Kirchhoff, Frank, Hahn, Beatrice H., Smith, Amos B., Pazgier, Marzena, Nussenzweig, Michel C., Kumar, Priti, Finzi, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703018/
https://www.ncbi.nlm.nih.gov/pubmed/36351384
http://dx.doi.org/10.1016/j.celrep.2022.111624