Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions

G-protein coupled receptor kinases (GRKs) participate in the regulation of chemokine receptors by mediating receptor desensitization. They can be recruited to agonist-activated G-protein coupled receptors (GPCRs) and phosphorylate their intracellular parts, which eventually blocks signal propagation...

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Detalles Bibliográficos
Autores principales: Glaser, Katharina M., Tarrant, Teresa K., Lämmermann, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703078/
https://www.ncbi.nlm.nih.gov/pubmed/36451830
http://dx.doi.org/10.3389/fimmu.2022.1039803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703078/
https://www.ncbi.nlm.nih.gov/pubmed/36451830
http://dx.doi.org/10.3389/fimmu.2022.1039803

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