Immune gene expression analysis indicates the potential of a self-amplifying Covid-19 mRNA vaccine

Remarkable potency has been demonstrated for mRNA vaccines in reducing the global burden of the ongoing COVID-19 pandemic. An alternative form of the mRNA vaccine is the self-amplifying mRNA (sa-mRNA) vaccine, which encodes an alphavirus replicase that self-amplifies the full-length mRNA and SARS-Co...

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Detalles Bibliográficos
Autores principales: Ong, Eugenia Z., Yee, Jia Xin, Ooi, Justin S. G., Syenina, Ayesa, de Alwis, Ruklanthi, Chen, Shiwei, Sim, Jean X. Y., Kalimuddin, Shirin, Leong, Yan Shan, Chan, Yvonne F. Z., Sekulovich, Rose, Sullivan, Brian M., Lindert, Kelly, Sullivan, Sean B., Chivukula, Pad, Hughes, Steven G., Low, Jenny G., Ooi, Eng Eong, Chan, Kuan Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703414/
https://www.ncbi.nlm.nih.gov/pubmed/36443317
http://dx.doi.org/10.1038/s41541-022-00573-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703414/
https://www.ncbi.nlm.nih.gov/pubmed/36443317
http://dx.doi.org/10.1038/s41541-022-00573-y

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