Safety and efficacy of human polymerized hemoglobin on guinea pig resuscitation from hemorrhagic shock

For the past thirty years, hemoglobin-based oxygen carriers (HBOCs) have been under development as a red blood cell substitute. Side-effects such as vasoconstriction, oxidative injury, and cardiac toxicity have prevented clinical approval of HBOCs. Recently, high molecular weight (MW) polymerized hu...

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Detalles Bibliográficos
Autores principales: Muller, Cynthia R., Williams, Alexander T., Walser, Cynthia, Eaker, Allyn M., Sandoval, Jose Luis, Cuddington, Clayton T., Wolfe, Savannah R., Palmer, Andre F., Cabrales, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703428/
https://www.ncbi.nlm.nih.gov/pubmed/36443351
http://dx.doi.org/10.1038/s41598-022-23926-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703428/
https://www.ncbi.nlm.nih.gov/pubmed/36443351
http://dx.doi.org/10.1038/s41598-022-23926-y

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