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Safety and efficacy of human polymerized hemoglobin on guinea pig resuscitation from hemorrhagic shock
For the past thirty years, hemoglobin-based oxygen carriers (HBOCs) have been under development as a red blood cell substitute. Side-effects such as vasoconstriction, oxidative injury, and cardiac toxicity have prevented clinical approval of HBOCs. Recently, high molecular weight (MW) polymerized hu...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703428/ https://www.ncbi.nlm.nih.gov/pubmed/36443351 http://dx.doi.org/10.1038/s41598-022-23926-y |