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A p38α-BLIMP1 signalling pathway is essential for plasma cell differentiation

Plasma cells (PC) are antibody-secreting cells and terminal effectors in humoral responses. PCs differentiate directly from activated B cells in response to T cell-independent (TI) antigens or from germinal center B (GCB) cells in T cell-dependent (TD) antigen-induced humoral responses, both of whic...

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Detalles Bibliográficos
Autores principales: Wu, Jianfeng, Yang, Kang, Cai, Shaowei, Zhang, Xiaohan, Hu, Lichen, Lin, Fanjia, Wu, Su-qin, Xiao, Changchun, Liu, Wen-Hsien, Han, Jiahuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703440/
https://www.ncbi.nlm.nih.gov/pubmed/36443297
http://dx.doi.org/10.1038/s41467-022-34969-0