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CDX-301 prevents radiation-induced dysregulation of miRNA expression and biogenesis

Risks of radiation exposure necessitate the development of radioprophylactic drugs. We have reported the efficacy of CDX-301, a recombinantly developed human protein form of Fms-related tyrosine kinase 3 ligand (Flt3L), as a radioprophylactic and radiomitigatory agent. Here, we performed global micr...

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Detalles Bibliográficos
Autores principales: Soni, Dharmendra Kumar, Kumar, Vidya P., Biswas, Shukla, Holmes-Hampton, Gregory P., Bhattacharyya, Sharmistha, Thomas, Lawrence J., Biswas, Roopa, Ghosh, Sanchita P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703457/
https://www.ncbi.nlm.nih.gov/pubmed/36457703
http://dx.doi.org/10.1016/j.omtn.2022.11.010