Active site polymerase inhibitor nucleotides (ASPINs): Potential agents for chronic HBV cure regimens

Chronic hepatitis B virus (HBV) infection affects 240 to 300 million people worldwide. In the nucleus of infected hepatocytes, the HBV genome is converted to covalently closed circular DNA (cccDNA), which persists and serves as a transcriptional template for viral progeny. Therefore, a long-term cur...

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Detalles Bibliográficos
Autores principales: Gish, Robert G, Asselah, Tarik, Squires, Katherine, Mayers, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703507/
https://www.ncbi.nlm.nih.gov/pubmed/36423233
http://dx.doi.org/10.1177/20402066221138705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703507/
https://www.ncbi.nlm.nih.gov/pubmed/36423233
http://dx.doi.org/10.1177/20402066221138705

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