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Whole-genome sequencing of extrachromosomal circular DNA of cerebrospinal fluid of medulloblastoma

BACKGROUND: Medulloblastoma (MB) is a malignant tumor associated with a poor prognosis in part due to a lack of effective detection methods. Extrachromosomal circular DNA (eccDNA) has been associated with multiple tumors. Nonetheless, little is currently known on eccDNA in MB. METHODS: Genomic featu...

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Detalles Bibliográficos
Autores principales: Zhu, Yi, Liu, Zhihui, Guo, Yuduo, Li, Shenglun, Qu, Yanming, Dai, Lin, Chen, Yujia, Ning, Weihai, Zhang, Hongwei, Ma, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703567/
https://www.ncbi.nlm.nih.gov/pubmed/36452490
http://dx.doi.org/10.3389/fonc.2022.934159