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Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA

While cell-free DNA (cfDNA) is widely being investigated, free circulating RNA (extracellular RNA, exRNA) has the potential to improve cancer therapy response monitoring and detection due to its dynamic nature. However, it remains unclear in which blood subcompartment tumour-derived exRNAs primarily...

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Detalles Bibliográficos
Autores principales: Vermeirssen, Vanessa, Deleu, Jill, Morlion, Annelien, Everaert, Celine, De Wilde, Jilke, Anckaert, Jasper, Durinck, Kaat, Nuytens, Justine, Rishfi, Muhammad, Speleman, Frank, Van Droogenbroeck, Hanne, Verniers, Kimberly, Baietti, Maria Francesca, Albersen, Maarten, Leucci, Eleonora, Post, Edward, Best, Myron G, Van Maerken, Tom, De Wilde, Bram, Vandesompele, Jo, Decock, Anneleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703587/
https://www.ncbi.nlm.nih.gov/pubmed/36451702
http://dx.doi.org/10.1093/narcan/zcac037