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The role of oligomerization in the optimization of cyclohexadienyl dehydratase conformational dynamics and catalytic activity

The emergence of oligomers is common during the evolution and diversification of protein families, yet the selective advantage of oligomerization is often cryptic or unclear. Oligomerization can involve the formation of isologous head‐to‐head interfaces (e.g., in symmetrical dimers) or heterologous...

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Detalles Bibliográficos
Autores principales: East, Nicholas J., Clifton, Ben E., Jackson, Colin J., Kaczmarski, Joe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703590/
https://www.ncbi.nlm.nih.gov/pubmed/36382881
http://dx.doi.org/10.1002/pro.4510