The noncatalytic regions of the tyrosine kinase Tnk1 are important for activity and substrate specificity

Human Tnk1 (thirty-eight negative kinase 1) is a member of the Ack family of nonreceptor tyrosine kinases. Tnk1 contains a sterile alpha motif, a tyrosine kinase catalytic domain, an SH3 (Src homology 3) domain, and a large C-terminal region that contains a ubiquitin association domain. However, spe...

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Detalles Bibliográficos
Autores principales: Ahmed, Sultan, Miller, W. Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703632/
https://www.ncbi.nlm.nih.gov/pubmed/36334623
http://dx.doi.org/10.1016/j.jbc.2022.102664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703632/
https://www.ncbi.nlm.nih.gov/pubmed/36334623
http://dx.doi.org/10.1016/j.jbc.2022.102664

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