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Evaluating the frequency and the impact of pharmacogenetic alleles in an ancestrally diverse Biobank population

BACKGROUND: Pharmacogenomics (PGx) aims to utilize a patient’s genetic data to enable safer and more effective prescribing of medications. The Clinical Pharmacogenetics Implementation Consortium (CPIC) provides guidelines with strong evidence for 24 genes that affect 72 medications. Despite strong e...

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Detalles Bibliográficos
Autores principales: Verma, Shefali S., Keat, Karl, Li, Binglan, Hoffecker, Glenda, Risman, Marjorie, Sangkuhl, Katrin, Whirl-Carrillo, Michelle, Dudek, Scott, Verma, Anurag, Klein, Teri E., Ritchie, Marylyn D., Tuteja, Sony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703665/
https://www.ncbi.nlm.nih.gov/pubmed/36443877
http://dx.doi.org/10.1186/s12967-022-03745-5