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Epigenetic modification of miR-217 promotes intervertebral disc degeneration by targeting the FBXO21-ERK signalling pathway

BACKGROUND: Numerous potential therapeutic alternatives for intervertebral disc degeneration (IDD) have been investigated, the most promising of which are based on biological variables such as microRNAs (miRNAs). Therefore, we verified the hypothesis that miRNAs modulate IDD by affecting the FBXO21-...

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Detalles Bibliográficos
Autores principales: Chen, Zhonghui, Ming, Jianghua, Liu, Yajing, Hu, Geliang, Liao, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703697/
https://www.ncbi.nlm.nih.gov/pubmed/36443856
http://dx.doi.org/10.1186/s13075-022-02949-w