Cross-regulome profiling of RNA polymerases highlights the regulatory role of polymerase III on mRNA transcription by maintaining local chromatin architecture

BACKGROUND: Mammalian cells have three types of RNA polymerases (Pols), Pol I, II, and III. However, the extent to which these polymerases are cross-regulated and the underlying mechanisms remain unclear. RESULTS: We employ genome-wide profiling after acute depletion of Pol I, Pol II, or Pol III to...

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Detalles Bibliográficos
Autores principales: Jiang, Yongpeng, Huang, Jie, Tian, Kai, Yi, Xiao, Zheng, Haonan, Zhu, Yi, Guo, Tiannan, Ji, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703767/
https://www.ncbi.nlm.nih.gov/pubmed/36443871
http://dx.doi.org/10.1186/s13059-022-02812-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703767/
https://www.ncbi.nlm.nih.gov/pubmed/36443871
http://dx.doi.org/10.1186/s13059-022-02812-w

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