GWAS of thyroid dysgenesis identifies a risk locus at 2q33.3 linked to regulation of Wnt signaling

Congenital hypothyroidism due to thyroid dysgenesis (TD), presented as thyroid aplasia, hypoplasia or ectopia, is one of the most prevalent rare diseases with an isolated organ malformation. The pathogenesis of TD is largely unknown, although a genetic predisposition has been suggested. We performed...

Descripción completa

Detalles Bibliográficos
Autores principales: Narumi, Satoshi, Opitz, Robert, Nagasaki, Keisuke, Muroya, Koji, Asakura, Yumi, Adachi, Masanori, Abe, Kiyomi, Sugisawa, Chiho, Kühnen, Peter, Ishii, Tomohiro, Nöthen, Markus M, Krude, Heiko, Hasegawa, Tomonobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Association Studies Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703809/
https://www.ncbi.nlm.nih.gov/pubmed/35535691
http://dx.doi.org/10.1093/hmg/ddac093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703809/
https://www.ncbi.nlm.nih.gov/pubmed/35535691
http://dx.doi.org/10.1093/hmg/ddac093

Ejemplares similares