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Comparative genomic analyses of multiple backcross mouse populations suggest SGCG as a novel potential obesity-modifier gene

To nominate novel disease genes for obesity and type 2 diabetes (T2D), we recently generated two mouse backcross populations of the T2D-susceptible New Zealand Obese (NZO/HI) mouse strain and two genetically different, lean and T2D-resistant strains, 129P2/OlaHsd and C3HeB/FeJ. Comparative linkage a...

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Detalles Bibliográficos
Autores principales: Kuhn, Tanja, Kaiser, Katharina, Lebek, Sandra, Altenhofen, Delsi, Knebel, Birgit, Herwig, Ralf, Rasche, Axel, Pelligra, Angela, Görigk, Sarah, Khuong, Jenny Minh-An, Vogel, Heike, Schürmann, Annette, Blüher, Matthias, Chadt, Alexandra, Al-Hasani, Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703946/
https://www.ncbi.nlm.nih.gov/pubmed/35796564
http://dx.doi.org/10.1093/hmg/ddac150