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Simple synthesis of multi-halogenated alkenes from 2-bromo-2-chloro-1,1,1-trifluoroethane (halothane)

A series of aryl fluoroalkenyl ethers that contain chlorine and bromine as well as fluorine atoms were prepared in moderate to good yields via the reactions of phenols and 2-bromo-2-chloro-1,1,1-trifluoroethane (halothane) in the presence of KOH. This simple reaction enabled the construction of high...

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Detalles Bibliográficos
Autores principales: Karuo, Yukiko, Tarui, Atsushi, Sato, Kazuyuki, Kawai, Kentaro, Omote, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704012/
https://www.ncbi.nlm.nih.gov/pubmed/36483094
http://dx.doi.org/10.3762/bjoc.18.167