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Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and release kinetics

Intestinal cancers are the third most lethal cancers globally, beginning as polyps in the intestine and spreading with a severe metastatic tendency. Chemotherapeutic drugs used in the treatment of intestinal tumors are usually formulated for parenteral administration due to poor solubility and bioav...

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Detalles Bibliográficos
Autores principales: Ünal, Sedat, Doğan, Osman, Aktaş, Yeşim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704015/
https://www.ncbi.nlm.nih.gov/pubmed/36483636
http://dx.doi.org/10.3762/bjnano.13.115